Shane Crotty - Vaccines

Author Information

Shane Crotty is affiliated with multiple prestigious institutions, including the Division of Vaccine Discovery at La Jolla Institute for Immunology (LJI), the Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery (Scripps CHAVI-ID) at The Scripps Research Institute, and the Department of Medicine at the University of California, San Diego. His work focuses on immunology and vaccine discovery, with significant contributions to understanding immune responses to various pathogens.

Research Contributions

In 2022 alone, Shane Crotty published numerous impactful papers. His research spans from the neutralizing activity of antibodies against HIV and SARS-CoV-2 to the development of T cell-based immunodiagnostic systems. Key studies include examining the effectiveness of various COVID-19 vaccines against different SARS-CoV-2 variants, understanding T cell memory post-vaccination, and using cryo-electron microscopy for antibody discovery. His work is instrumental in advancing our understanding of both humoral and cellular immunity in infectious diseases.

Aliases

Shane Crotty is also known by several aliases, including S Crotty and S. Crotty.

Publication and Citation Metrics

Metric	Value
Total Citation Count	42,015
h-index	95
Paper Count	331

Publications:

Highly mutated antibodies capable of neutralizing N276 glycan-deficient HIV after a single immunization with an Env trimer

DOI: 10.1016/j.celrep.2022.110485

Year: 2022

Omicron BA.1 and BA.2 neutralizing activity elicited by a comprehensive panel of human vaccines

DOI: 10.1101/2022.03.15.484542

Year: 2022

SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron

DOI: 10.1016/j.cell.2022.01.015

Year: 2022

From structure to sequence: Antibody discovery using cryoEM

DOI: 10.1126/sciadv.abk2039

Year: 2022

Development of a T cell-based immunodiagnostic system to effectively distinguish SARS-CoV-2 infection and COVID-19 vaccination status

DOI: 10.1016/j.chom.2022.02.003

Year: 2022

Observations and perspectives on adaptive immunity to SARS-CoV-2.

DOI: 10.1093/cid/ciac310

Year: 2022

Correction to: Increased Peripheral Blood Neutrophil Activation Phenotypes and Neutrophil Extracellular Trap Formation in Critically Ill Coronavirus Disease 2019 Patients: A Case Series and Review of the Literature.

DOI: 10.1093/cid/ciac216

Year: 2022

NVX-CoV2373 vaccination induces functional SARS-CoV-2–specific CD4+ and CD8+ T cell responses

DOI: 10.1101/2022.04.08.487674

Year: 2022

Humoral and cellular immune memory to four COVID-19 vaccines

DOI: 10.1101/2022.03.18.484953

Year: 2022

SARS-CoV-2 infection generates tissue-localized immunological memory in humans

DOI: 10.1126/sciimmunol.abl9105

Year: 2021

What is Immunity?

What Challenges Do mRNA Vaccines Face?

What are the Types of Hib Vaccines?

Is the HPV Vaccine Effective?

How Can the Public Contribute to Pharmacovigilance?

What Should You Do If a Dose is Missed?

How Do B Cells Work?

How Do Recombinant Protein Vaccines Work?

How does the CDC support global vaccination efforts?

What is Genetic Engineering in Vaccinology?

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