What are the Applications of NGS in Vaccine Research?
1. Pathogen Discovery and Surveillance: NGS helps in identifying new pathogens and monitoring existing ones for genetic mutations that may affect vaccine efficacy. 2. Antigen Identification: By sequencing the genomes of pathogens, researchers can identify potential antigens that could serve as vaccine targets. 3. Vaccine Efficacy and Safety: NGS can be used to analyze the genetic response of the host to the vaccine, ensuring it elicits the desired immune response without adverse effects. 4. Genetic Variability: It tracks the genetic drift and shift in viruses, which is crucial for developing effective vaccines, especially for rapidly mutating viruses like influenza and SARS-CoV-2.
