What are the Challenges with T Cell Activation in Vaccines?
While T cells are crucial for effective vaccination, there are challenges in designing vaccines that effectively elicit a T cell response. Some pathogens, such as HIV and Hepatitis C, can evade the immune system by mutating rapidly, making it difficult for T cells to recognize them. Additionally, the effectiveness of T cell responses can be compromised in individuals with weakened immune systems, such as the elderly or those with immunodeficiencies.
